My latest work:
I work on proteins that control energy balance- fuel sensors, if you like- and one of the proteins that I work on seems to be regulating energy balance by its action in different parts of the body. For example, we have shown that this protein controls the work of the cells in the pancreas that regulate glucose balance and that people with type 2 diabetes have lowered levels of this protein in these cells. Recently, I found that mice that lack this fuel sensor eat more, and they eat more at the wrong time of day, suggesting that this protein is important in regulating appetite and responses to hunger. I am currently trying to figure out how this protein is doing this.